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Apart from naloxone, the two new agents available on the market to reverse opiate toxicity are nalmefene. Nalmefene features a 50 %-life of 4 to eight hrs. Even so, the regime use of this for a longer period-performing opiate antagonist isn't advisable because of the anxiety of precipitating a chronic period of opiate withdrawal.[thirty] The usage
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Providing there are no contraindications, activated charcoal must be administered to all symptomatic individuals with opiate overdose. If the medical professional suspects that the individual has overdosed on an opiate and it has indications of respiratory and CNS melancholy, no time ought to be squandered on laboratory studies; instead, naloxone